三叶青抗病毒研究

王茅6353*醉美酱香*陨石馆

<h3>三叶青是中国特有珍稀名贵的中药,主要分布在长江以南,以福建为主,是福建地区传统习用青草药。</h3> <h3>化学研究表明三叶青主要含有异荭草素、荭草素、牡荆素鼠李糖苷、牡荆素、异牡荆素等碳苷类化合物,北京中医药大学的研究表明牡荆素、荭草素能够通过影响流感病毒活性而发挥抗病毒作用。</h3> <h3>中国科学院****研究所利用三叶青提取物治疗感染仙台病毒、流感病毒和滤泡性口炎病毒的小白鼠和鸡胚成纤维细胞来研究三叶青抗病毒作用,试验结果表明:三叶青提取物无论在组织培养细胞上或小白鼠体内均显示出不同程度的抗病毒作用。在组织培养中,三叶青提取物能较强地抑制流感病毒的繁殖、对仙台病毒具有明显的抗病毒作用,对滤泡性口炎病毒有很强的抑制作用。在小白鼠试验中,由于小白鼠机体防卫系统的作用,调节功能完善,在一定的药物浓度范围内,三叶青提取物对流感及仙台病毒有较强的抗病毒效果。</h3><h3><br></h3><h3>《南京中医药大学学报》曾公开报道三叶青提取物能够对乙肝病毒的DNA具有显著的抑制作用,即在病毒复制水平就能抑制病毒的合成,药物浓度越高,抑制作用越强。</h3> <p style="max-width: 100%; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif; letter-spacing: 0.544px; text-align: justify; white-space: normal; text-indent: 32px; overflow-wrap: break-word !important;"><span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">山东中医药大学利用三叶青提取物对呼吸道合胞病毒的抑制作用进行研究,从而筛选出三叶青抗</span><strong style="max-width: 100%; overflow-wrap: break-word !important;"><span style="max-width: 100%; font-family: 宋体; background-color: rgb(115, 250, 121); overflow-wrap: break-word !important;">呼吸道合胞病毒</span></strong><span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">有效部位,并发现三叶青乙醇提取物正丁醇萃取部分和乙酸乙酯萃取部分的</span>TI<span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">值分别为</span>128<span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">和</span>64<span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">,相对于阳性对照药利巴韦林</span>(TI<span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">值为</span>6.25)<span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">。说明三叶青乙醇提取物正丁醇萃取部分和乙酸乙酯萃取部分具有抗呼吸道合胞病毒的活性且明显优于利巴韦林。</span></h3><p style="max-width: 100%; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif; letter-spacing: 0.544px; text-align: justify; white-space: normal; text-indent: 32px; overflow-wrap: break-word !important;"><span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">此外山东中医药大学还对人类免疫缺陷病毒(</span>HIV<span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">)活性的抑制作用进行研究。结果表明三叶青提取物对不同</span>HIV-1<span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">病毒株有不同程度的抑制作用,且可能是通过抑制</span>HIV-1<span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">病毒至细胞及</span>HIV-1<span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">逆转录酶活性达到抗</span>HIV<span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">活性的目的。</span></h3> <h3><span style="max-width: 100%; color: rgb(51, 51, 51); letter-spacing: 0.544px; text-align: justify; text-indent: 32px; white-space: normal; font-family: 宋体; overflow-wrap: break-word !important;">上述科研院所对三叶青提取物进行抗病毒作用研究,实验结果明确,</span><span style="max-width: 100%; letter-spacing: 0.544px; text-align: justify; text-indent: 32px; white-space: normal; font-family: 宋体; color: rgb(255, 76, 65); overflow-wrap: break-word !important;"><strong style="max-width: 100%; overflow-wrap: break-word !important;">三叶青能够对流感病毒、呼吸道合胞病毒、乙肝病毒、滤泡性口炎病毒和人类免疫缺陷病毒均具有较好的抑制作用</strong></span><span style="max-width: 100%; color: rgb(51, 51, 51); letter-spacing: 0.544px; text-align: justify; text-indent: 32px; white-space: normal; font-family: 宋体; overflow-wrap: break-word !important;"><strong style="max-width: 100%; overflow-wrap: break-word !important;">,</strong>这对中药三叶青应用于临床防治病毒病,尤其是对流感病毒的防治,提供了科学依据。</span><br></h3> <h3>抗疫情我们在行动✊,送亲朋,送好友,送三叶青,送健康。三叶青:在我国南方为民间常用药,其全株可入药,具有清热润肺、解毒、消炎、抗病毒、活血化瘀等功效。每天煮两包,全家抗病毒🙏需要随时联系18650088827香香<br></h3> <p style="max-width: 100%; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif; letter-spacing: 0.544px; text-align: justify; white-space: normal; text-indent: 32px; overflow-wrap: break-word !important;"><span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">参考文献:</span></h3><p style="max-width: 100%; clear: both; min-height: 1em; color: rgb(51, 51, 51); font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif; letter-spacing: 0.544px; text-align: justify; white-space: normal; text-indent: 32px; overflow-wrap: break-word !important;"><span style="max-width: 100%; font-size: 12px; overflow-wrap: break-word !important;">[1]<span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">王丹丹</span>,<span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">高荣</span>,<span style="max-width: 100%; font-family: 宋体; overflow-wrap: break-word !important;">闫滨</span>.<span style="max-width: 100%; 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